Black Lion Research: Follidrone, 90 Capsules

These days everyone already knows about Epicatechin so I wont spend alot of time here. Amazing stuff. There is a solid dose of Epicatechin in here along with a strong absorption enhancement package. BLR uses several ingredients that prevent metabolism and allow epicatechin to be fully absorbed which in turn increases its effects many times over. All the benefits you have come to love from epicatechin, Muscle mass, strength, endurance, pump but MUCH stronger.


Ecklonia Cava: EC

• Muscle mass

• Fat loss

• Promotes AMPK

• Increased Follistatin

• Reduced myostatin

• Reduded Activin A

• ACE inhibitor

• Antioxidant

• Vasodilator

• Cardio protective

• Increased brain function

• Reduced cholesterol

• GLUT4 Expression

This is one of the most well studied seaweeds on earth. Millions of dollars has been spent looking at this stuff for all kinds of purposes. Its exceptional with regards to health benefits and safety. Its also exceptional with regards to its benefits to us as muscle gain and fat loss enthusiasts. Like Epicatechin EC is a strong follistatin booster and as such myostatin inhibitor. In addition to its ability to reduce myostatin it is also a very solid ACE inhibitor. Ace inhibitors are interesting to say the very least. Ace inhibitors increase insulin sensitivity and glucose uptake into muscles. Lower ACE equates to lower overall bodyfat levels, increased fat metabolism in the liver and the ability to process sugars much faster. In addition increased cell surface GLUT4 increases nutrient shuttling into muscle tissue. It has been suggested that ACE inhibitor-induced positive effects may also be mediated by direct action on the skeletal muscle. In particular, two recently published observational studies documented that among hypertensive subjects free of CHF, treatment with ACE inhibitors was associated with better performance and muscular outcomes and genetic studies also support the hypothesis that the ACE system may be involved in physical performance and skeletal muscle function. Effects on the skeletal muscle are probably mediated by mechanical, metabolic, anti-inflammatory, nutritional, neurological and angiogenetic actions. Individuals with the II genotype of the ACE gene have greater endurance and greater skeletal muscle trainability in some studies. Hypertensive patients taking ACE inhibitors have greater cross-sectional muscle mass and a slower decline in walking speed than those taking other antihypertensives in epidemiological studies. ACE inhibitors are also known to improve endothelial function, muscle glucose uptake, increase potassium levels and modulate other hormonal systems including IGF-1, all of which could contribute to improved skeletal muscle function. Finally, ACE inhibitors could of course be mediating a direct effect on skeletal muscle structure and function; they are known to have trophic effects on myocardial tissue. Finally ACE inhibitors help us with fat loss independent of food intake. This appears to be due to a high energy expenditure related to increased metabolism of fatty acids in the liver, with the additional effect of increased glucose tolerance.

DGAT Inhibition
Diacylglycerol acetyl transferase (DGAT) is the enzyme involved in the final step of triglyceride synthesis. Triglycerides are circulating fat bodies that ultimately wind up in the fat cells, and are almost always elevated in diabetes. They also have emerged as a major risk factor in vascular disease.
It was found that EC compounds inhibited DGAT more than 50%. In genetically caused obese laboratory rats, EC reduced body fat and increased physical activity. In another study, EC caused leanness and fat-resistance in animals given a high fat diet.


Flos carth

• Increased Follistatin

• Reduced myostatin

• Reduded Activin A

• antiinflammitory

• antioxidant

• Increased NO production

Flos Carthami extract was initially a target for me because of its ability to increase Follistatin (see Fig 1.). Increased Follistatin, decreased Myostatin and activin A lead to increased muscle building potential. Flos Carthami has a strong antioxidant effect and is highly anti inflammatory. More than one tester mentioned a reduction in overall muscular pain perception acutely post training and during the DOMS stage of recovery. Several studies indicate that FC improves endothelial function and NO production similar to EC and (-)-E extract.


ABSORPTION PACKAGE

• Quercetin/niacin co crystal

• Vasodilator, Increased VO2 Max